The effect of hydro-alcoholic celery (Apium graveolens) leaf extract on cardiovascular parameters and lipid profile in animal model of hypertension induced by. Abstract: Apium graveolens (celery) is an edible and traditionally medicinal plant worldwide, among others for the treatment of hypertension. Celery (Apium graveolens L., Apiaceae) is one of the popular aromatic mean arterial blood pressure and heart rate in normotensive and hypertensive rats.

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Flavonoids are noted for their vasorelaxant responses, including flow-mediated Ras et al. Another mechanism that may explain the hypotensive effect of black cumin pertains to its diuretic action Zaoui et al. Cardioprotective effect of saffron extract and safranal in isoproterenol-induced myocardial infarction in wistar rats. Thymoquinone inhibits phorbol ester-induced activation of NF-kappaB and expression of COX-2, and induces expression of cytoprotective enzymes in mouse skin in vivo.

Green tea attenuates oxidative stress and downregulates the expression of angiotensin II AT 1 receptor in renal and hepatic tissues of streptozotocin-induced diabetic rats.

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Male Wistar rat thoracic aorta. The aforemnetioned antihypertensive actions are credited to the plant’s multiple components: Garlic and onion attenuates vascular inflammation and oxidative stress in fructose-fed rats. A combination treatment of danshen and gegen Pueraria lobata was shown to lower blood pressure in SHRs Ng et al. In several countries, coriander also known as cilantro or dhania is not only used as a culinary ingredient Anilakumar et al. Peer review In this good study, the authors performed antihypertensive activity of A.


Antihypertensive Effect of Celery Seed on Rat Blood Pressure in Chronic Administration

Sprague Dawley rats were divided into five groups: Cardiovascular and metabolic effects of Berberine. Moreover, WS caused endothelium-dependent and NO-mediated vasorelaxation of phenylephrine-preconstricted rings of rat aorta as well as human internal mammaria Brixius et al. Effect of hawthorn standardized extract on flow mediated dilation in prehypertensive and mildly hypertensive adults: Statistical analysis showed a significant difference between all treatment groups hexanic, methanolic, and aqueous-ethanolic extract and negative control groups.

Involvement of Rab28 in NF-kappaB nuclear transport in endothelial cells.

Stage 1 and 2 hypertension. Iran J Kidney Dis, 2 1: The inhibition of calcium entry from extracellular sources was also responsible for apigenin-dependent relaxation of noradrenaline-preconstricted rat isolated aorta.

CAM’s outstanding contribution to modern therapeutics. Hypotensive and vasorelaxant effects of citronellol, a monoterpene alcohol, in rats.

Combating oxidative stress in vascular disease: However, endothelial derangement could be reversed by modification therapy, such as with herbal remedies. Use of antihypertensive drugs in France and relationship graveolfns cardiovascular disease. Natural antioxidants and hypertension: Health Care Poor Underserved 22— Saffron’s antioxidant ability has also been widely reported.

Green tea has been reported to increase CAT antioxidant enzyme while simultaneously blocking AT 1 receptors in streptozotocin-treated rats Thomson et al.

Anti-hypertensive Herbs and their Mechanisms of Action: Part I

Natural antioxidants from tomato extract reduce blood pressure in patients with grade-1 hypertension: An increase in the amount of ROS, and the corresponding fall in intracellular endothelial antioxidant levels Zeng et al. Safety evaluation of saffron Crocus sativus tablets in healthy volunteers.


Coriandrum sativum cilantro or coriander In several countries, coriander also known as cilantro or dhania is not only used as a culinary ingredient Anilakumar et al. Apiumgraveolens modulates sodium valproate-induced reproductive toxicity in rats. Human aortic smooth muscle cells. Saffron common namea plant indigenous to Southwest Asia Iran, Pakistan, and IndiaSpain, Greece, and Morocco, is a stemless herb whose medicinal values have been sought for over years Srivastava et al.

Nigella sativa and its protective role in oxidative stress and hypertension.

Moreover, arteries denuded of endothelium were not reliant on tetraethylammonium-dependent potassium channels. Notes Comments Background A. Such effects appear to be mediated by an increase in diuretic activity, efflux of water and sodium, as well as expression of NOS enzyme. Methanol extract from A.

Endothelium-dependent and-independent relaxation induced by pinocembrin in rat aortic rings. Isoproterenol-induced cardiotoxicity in male Wistar rats. In addition to its antioxidant Lobo et al. Support Center Support Center. Rat isolated cardiomyocytes insulin-induced hypertrophy.

Comparative pharmacological investigations of Allium ursinum and Allium sativum. Hypotensive effect of aqueous saffron extract Crocus sativus L. Cardiovascular activity of Labdane Diterpenes from andrographis paniculata in isolated rat hearts.