Malar J. Nov 26;17(1) doi: /sy. Aspidosperma pyrifolium, a medicinal plant from the Brazilian caatinga, displays a high. Aspidosperma pyrifolium Has Anti-Inflammatory Properties: An Experimental Study in Mice with Peritonitis Induced by Tityus serrulatus Venom or Carrageenan. Find technical and marketing information for lesser-used tropical timber species, LUS. Learn more on our Jitichuriqui (Aspidosperma pyrifolium) page.

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The present study was conducted to evaluate the protective ability of aqueous extract from the aspudosperma of Aspidosperma pyrifolium against inflammation induced by carrageenan and Tityus serrulatus scorpion venom. Leukocytes are involved in organism defense, and their migration into the tissue is a crucial process during host response against microorganism infections and injurious agents [ 33 ].

This is the first study focusing on the ability of rutin and pyrlfolium extracts of A.

Introduction The scorpion genus Tityus is responsible for the majority of scorpion envenomation in Brazil, and, in particular, the species Tityus serrulatus Buthidae is the most common and harmful. In part, these clinical manifestations may be observed by the presence of neurotoxic components in the venom which interact with sodium and potassium channels in nerve endings [ 78 ]. These findings corroborate previous studies demonstrating that anti-inflammatory effect is a common property of plants from the Apocynaceae family [ 173239 ].

Conflicts of Interest The authors declare no conflict of interest. Stake Posts 5 – Propriedades fisicas e mecanicas da madeira e do contraplacado de Pinus elliottii.

This article is an open access article distributed under the terms aspidoslerma conditions of the Creative Commons Attribution CC BY license http: The use of T. Another record of significant regional variation in toxicity of Tityus serrulatus venom in Brazil: The experiment was performed in triplicate. John Wiley; Chichester, UK: Popular reports in farms in the State of Rio Grande do Norte, Brazil, described that the old-aged-people used the species for the aspidosperms of dizziness, urinary disorders, wound healing and inflammation.


Sawing Cutting behavior is reported to be fair to difficult.

Aspidosperma pyrifolium, also a medicinal plant, is used as a natural anti-inflammatory. Anti-inflammatory activity of aqueous extract AE from the leaves of Aspidosperma pyrifolium and rutin against Tityus serrulatus venom-induced peritonitis model.

The authors acknowledge all participants for their valuable time and commitment to the study. Enzymatic properties of venoms from Brazilian scorpions of Tityus genus and the neutralisation potential of therapeutical antivenoms. A step towards understanding the possible role of sodium channel modulators. Flooring 14 – Handbook of Hardwoods. Previous studies of chemical composition of A.

Scientific Name Synonyms Macaglia pyrifolia Mart. Vessels per mm2 more than 20 very abundant. Time-kinetics of VTs-induced inflammation and of rutin treatment on the envenomation-induced peritonitis model in mice. Further studies are required to test the potential application of this extract and identified compound in the therapy of inflammatory conditions and of scorpion envenomation.

Aspidosperma pyrifolium Images

Compounds 67 and 8 correspond to chlorogenic acid isomers, n -chlogenic, crypto-chlorogenic and iso-chlorogenic acid, respectively. The Handbook of Natural Flavonoids. In this study, the effect of A. Figure 4 A shows that the dose of 7.

Aspidosperma pyrifolium – Useful Tropical Plants

The main results confirmed its anti-inflammatory effect in two models of peritonitis at all doses tested 2, 2. Abstract Scorpions of the genus Tityus are responsible for the majority of envenomation in Brazil, the Tityus serrulatus species being the most common and dangerous in South America.

Scorpion venom and the inflammatory response. Poles 3 – Estudo dendrologico e determinacao das caracteristicas fisicas e mecanicas do genipapo Zspidosperma americana. The AE was analyzed in triplicate.


Fact Sheet: Aspidosperma pyrifolium

Truck Body 53 – Timbers of the New World. Ipomoea asarifolia neutralizes inflammation induced by Tityus serrulatus scorpion venom. Flavonoids as medicinal aspisosperma Please review our privacy policy. For in vivo studies in carrageenan-induced peritonitis model, mice received extracts, dexamethasone, rutin or saline, before administration of carrageenan. The pathogenesis of such edema is very complex; envenoming by this species can be severe, and lead to death caused by acute pulmonary edema [ 56 ].

Scientific Name Aspidosperma pyrifolium Mart. Alkaloids of Aspidosperma pyrifolium. Find articles by Ruth Medeiros Oliveira.

Carrageenan-induced peritonitis assay was performed according to the procedure described by Longhi-Balbinot et al. The rutin show numerous interesting biological activities, for example, antioxidant capacity, anti-inflammatory action and stimulation of the immune system [ 2324 ].

Then, the medium was replaced by serum-free medium for synchronizing the cell cycle in G0 phase. After six hours of envenomation induction, the mice were euthanized; 2 mL of cold sterile saline were injected in the peritoneal cavity and, after 30 s of gentle massaging, peritoneal fluid was collected.

In the group treated with serum arachnid antivenom, the number of inflammatory cells surrounding the bronchi and bronchioles and the alveolar wall thickness presented a similar histomorphological appearance as the saline group. The solvents used were HPLC-grade and ultra-pure water. The analyses of AE A.

In isomers compounds 12 and 13it is not possible to identify the position of caffeic aspodosperma residues. This is an original study revealing the potential action of A.