The chloroform extract of the leaves of Caesalpinia pyramidalis (Caesalpinioidea , Fabaceae) yielded the new biflavonoid named caesalflavone, as well as. Recebido em 17/9/09; aceito em 2/2/10; publicado na web em 18/6/10 The chloroform partition of methanol extract of leaves of Caesalpinia. PDF | The chloroform extract of the leaves of Caesalpinia pyramidalis ( Caesalpinioidea, Fabaceae) yielded the new biflavonoid named caesalflavone, as well as.
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The highest concentrations of IgA were detected in samples from G3 and G4.
The active principles for the anthelmintic effect of C. Moreover, the serum anti- Haemonchus antibody responses presented significant increases in G2 and G3, whereas G4 yielded an average OD of 1.
On the other hand, the flavanone unit was recognized by its characteristic 13 C signals, which were attributed to a carbonyl group as caesalpihia as to the C-2 and oxybenzylic carbon of ring C. The mechanisms whereby the consumption of certain plants and plant extracts can affect parasite cycle both in vitro and in vivo are unknown.
Mean number of nematode pyramidali per gram of faeces in naturally infected goats a and mean live weight b along the experimental period. The chloroform partition How to cite this article. Goats were traditional grazing under extensive management practices in the Caesalpimia semiarid region and had naturally acquired gastrointestinal nematode infection, being confirmed prior the experiment beginning by faeces egg count FEC average values before starting the trial G: The genus Caesalpinia Caesalpinioideae, Fabaceaecomprised of tropical or subtropical pyramivalis or shrubs, contains more than species worldwide.
However, the analysis of HMBC spectrum data for the linkage between the flavonoid units was conclusive. The absence of bathochromic effect permitted to localize the methoxyl group in the C-2′. For leukocyte counts, similar results were observed in the posttreatment groups and also no significant differences were seen in the eosinophil values in blood when compared to the negative and pyramidqlis control. Thus, the single signal at d 5. The egg excretion pattern was similar for the positive control G2 and treated groups G3 and G4.
Material and Methods 2. This response could be partly explained by the CP chemical composition.
The parasitological analysis indicated that the CP extract exhibited anthelmintic activity in naturally infected goats, whose effectiveness was evidenced by the reduction in FEC as compared to the negative control group. The existence of a 1,4-dissubstituted ring B was shown by characteristic doublets d 7.
Dry trunk wood 5. Pyramidalsi appears that the IgA response caesalipnia involved with the generation of protective immunity against GIN, as parasitological data remained low in animals from G3 and G4 throughout the experiment.
However, its phytochemical analysis revealed the presence of different chemical compounds, among them polyphenols, like tannins and flavonoids [ 1112 ], that could be considered as the responsible for this bioactivity [ 1617 ].
Animals were weighed average weight before starting the trial G1: A possible explanation of this reduction may be due to the direct effect puramidalis CP extract pyramidalks parasite leading to drop in FEC in natural infected goats. In conclusion, the results showed that CP provoked a protective response in infected animals treated with them. The role of these substances needs to be better established because plants with anthelmintic properties can be one key factor to the control of nematode infections, whereas a number of medicinal plants have been used to treat parasitic infections in man and animals [ 417 ].
A significant increase in IgA levels was observed in G4, while low levels of IgG were observed in pyramidali G3 and G4, corresponding to the pyranidalis treated with the CP extract. The present work describes the phytochemical reexamination of the chloroform extract from leaves and trunk wood of C.
However, the G4 gained a significant difference in body weight Figure 1 b. Species identification was kindly provided by Prof. Pyramidalia concentration appears to be the most efficient.
Once some plants have been reported to have anthelmintic properties, attributed to secondary metabolites e. The antiulcer assays were performed using the ethanol- and nonsteroidal anti-inflammatory drug-induced ulcer models.
Significant differences are indicated by an asterisk marks. Probably the higher deviations on the determined FEC values were due to the traditional and extensive management practices in the Brazilian semiarid region; therefore, the goats were always exposed to a contaminated pyramidxlis.
The anthelmintic doramectin and the extract were administered through three consecutive days from the time zero. The chloroform extract of the leaves of Caesalpinia pyramidalis Caesalpinioidea, Fabaceae yielded the new biflavonoid named caesalflavone, as well as podocarpusflavone A, agathisflavone, apigenin and kaempferol.
However, the gastroprotective properties of this species have not yet been studied. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.
A new biflavonoid named caesalflavone 1 was isolated, along with caeesalpinia known compounds podocarpusflavona A 2agathisflavone 3apigenin, and kaempferol. However, the G4 animals treated with 5. Thus, the correlations observed between the peaks displayed at d 7. From the chloroform extract trunk wood were obtained the known compounds 4,4′-dihydroxy-2′-methoxychalcone 4syringaresinol caesapiniaand methyl gallate.
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Caesalpinia pyramidalis – Wikipedia
The HMQC spectrum was elucidative because it was possible to verify the correlations of pyarmidalis hydrogen signals and two carbon resonances each. In the model ligature pylorus, the treatment with Caesalpinia pyramidalis ethanol extract failed to significantly change the gastric secretion parameters.
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