Holothoria atra, is a holothurian of order Aspidochirotes belonging to the family Description a Sea Cucumber Species Holothuria atra Jaeger, from. Native range | All suitable habitat | Point map | Year This map was computer-generated and has not yet been reviewed. Holothuria atra AquaMaps Data. Holothuria (Holothuria) atra Jaeger, AphiaID. (urn:lsid: :taxname). Classification. Biota; Animalia.

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These results will direct future efforts to optimize the anti proliferative activity of these bioactive compounds. Articles from SpringerPlus are provided here courtesy of Springer-Verlag. The saponins isolated from the aqueous and methanolic extract of sea cucumber Holothuria forskali have showed considerable antiviral activities Mulloy et al. The species is fished in some parts of its range, but the holothuriq product is of low commercial value.

The antiviral activity using the sea cucumber Ludwigothurea grisea and Thelenota ananas derived fucosylated chondroitin sulfates FCSwas recognized as the sulfated polysaccharides. The culture sample was mixed to resuspend cells. Am J Clin Path. The mouth is on the underside at one end and is surrounded by a fringe of 20, black, branched tentacles.

IUCN Red List of Threatened Species

The structure of bioactive compounds was elucidated by using NMR spectra from the active fractions. The active fractions obtained from column chromatography were analysed for Nuclear magnetic resonance spectroscopy NMR analysis.

The plaques were counted by visual examination and the percentage of plaque inhibition was calculated. Virus dilutions were prepared in Eagles minimum essential medium. It was placed in the subgenus Halodeima by Pearson inmaking its full scientific name Holothuria Halodeima atra.

Saponins the secondary metabolites which are triterpene glycosides present in sea cucumbers like H. The Black Sea Cucumber, the most commonly encountered holothurian in Qatar, is an omnivore feeder, sifting through the sediment with its tentacles and feeding on detritus and other organic holothurria while at the same time hollothuria sand grains.


The authors are grateful and thankful to Dr. Sphingoid base composition of cerebrosides from sea cucumber Stichopus variegatus exhibited cytotoxicity against human colon cancer cell and induced apoptosis.

Percentage of growth inhibition was identified at different concentration of the extracts. Fisons GC series and MS: The online version of this article doi: Studies on sterol sulfate, sterol glycoside and cerebroside of sea cucumber Stichopus japonicus. Kerr RG, Chen Z. Zoogeography and systematic of holothurians used for Beche-de-mer in India, Proc. The GC column dimension was: It favours reef flats where it is not fully exposed to the waves but the water is holothuri aerated, and shallows beside slabs of rock from under which cool water wells out when the tide retreats.

Steroid glycosides are a class of wide-spread natural products having marine origins. Inhibitory action of Holothuria atra extracts against HSV strains -?

The potential angiogenesis inhibitors, a novel sulfated saponin philinopside A, isolated from the sea cucumber Pentacta quandrangularipossessed dual antiangiogenic and antitumour effects Tong et al.

The mechanism by which they block tumor growth is driven by the inhibition of receptor tyrosine kinases RTKs that are over expressed by cancer cells Chi In vivo and in vitro biosynthesis of saponins in sea cucumbers. Research results showed that angiogenesis inhibitors effectively block the growth of tumors by cutting off their nutrient and blood supply. Previous work showed that sulphated polysaccharides such as glycosaminoglycans an inhibitor of human immunodeficiency virus binds to T lymphocytes and showed antiviral activity Toido et al.


Sea Cucumbers atfa Northern Australia. Angiogenesis inhibitors and aromatase inhibitors present atga sea cucumbers play a major role in reducing the growth of breast cancer and prostate cancers, especially the solid tumors. Introduction The marine holothurians atrw spiny skinned invertebrates, which form important commercial group among the echinoderms. Results indicated that the anti proliferative effect increased with the increase in concentration of the extracts.

Benefits of a sea cucumber extract in anti-angiogenic therapy and RTK inhibition for cancer. Acknowledgments The authors are grateful and atrq to Dr.

Holothuria atra

The coverslip was fixed on the centre top of the hemocytometer. Class — sea cucumbers, Holothuroidea; order — Aspidochirotida; family — holothuriids, Holothuriidae.

It also showed the appearance of two carbon signals. Devaraj Isaac Dhinakaran, Email: World Register of Marine Species. Specimens of this species are conspicuous and aatra, lying exposed on sand flats of sandy or sand-covered rocky areas, sea grass beds, and among corals at depths from near the surface to about 20 m.

In India, about species of holothurians are known of which 75 species are from shallow waters within 20 m depths Cuvillier Free sterol compositions from the sea cucumbers Pseudostichopus trachus, Holothuria Microtele nobilis, Holothuria hilothuria, Trochostoma orientale and Bathyplotes natans.

SJG-1 exhibited neuritogenic activity towards the rat pheochromocytoma cell line PC12 cells in the presence of nerve growth factor Kaneko et al. Bioorg Med Chem Lett. The GC-MS analysis revealed the presence of 59 compounds.