KAPVAY PACKAGE INSERT PDF

KAPVAY PACKAGE INSERT PDF

Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Kapvay (clonidine). Concordia Pharmaceuticals Inc.: KAPVAY (clonidine hydrochloride) extended- release is indicated for the treatment of attention deficit. The following text is taken verbatim from the Kapvay package insert: “The dose of Kapvay [ER clonidine], administered either as monotherapy or as adjunctive.

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Especially tell your doctor if you take: The dose was maintained for a minimum of 2 weeks before being gradually tapered to 0. Measure heart rate and blood pressure prior to initiation of therapy, following dose increases, and periodically while on therapy. These doses are approximately 20, 25, and 15 times, respectively, lapvay maximum recommended human dose MRHD of 0.

Clonidine is in a class of medications called centrally acting alpha-agonist hypotensive agents. To avoid this problem, get out of bed slowly, resting your feet on the floor for a few minutes before standing up.

Clonidine: MedlinePlus Drug Information

Caution is warranted in patients receiving clonidine concomitantly with agents known to affect sinus node function or AV nodal conduction e. Clonidine hydrochloride is an odorless, bitter, white, crystalline substance soluble in water and alcohol.

Generic alternatives may be available. When inert treatment, provide dosage escalation instructions [see Dosage and Administration 2. Clonidine may potentiate the CNS-depressive effects of alcohol, barbiturates or other sedating drugs.

Reactions have packxge generalized paxkage, urticaria, and angioedema [see Adverse Reactions 6 ]. If you become pregnant while taking clonidine, call your doctor. The maximum placebo-subtracted mean change in diastolic blood pressure was Effect on Blood Pressure and Heart Rate In patients that completed 5 weeks of treatment in a controlled, fixed-dose monotherapy study in pediatric patients, during the treatment period the maximum placebo-subtracted mean change in systolic blood pressure was There may be new information.

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Kavay sure to mention any of the following: Although studies of the effect of renal impairment and studies of clonidine excretion have not been performed with KAPVAY, results are likely to be similar to those of the immediate release formulation. By stimulating alpha 2 -adrenergic receptors in the brain stem, clonidine reduces sympathetic outflow from the central nervous system and decreases peripheral resistance, renal vascular resistance, heart rate, and blood pressure.

Mean concentration-time data from the 3 treatments are shown in Table 7 and Figure 1. Titrate KAPVAY slowly and monitor vital signs frequently in patients with cardiac conduction abnormalities or patients concomitantly treated with other sympatholytic drugs.

You may need a different medicine. The following is the structural formula: Clonidine may help to control your condition but will not cure it. The most common adverse reactions that led to discontinuation were somnolence and fatigue.

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Double-Blind Full Analysis Set. Patients were randomly assigned insetr one of two treatment groups: Other uses for this medicine. If the victim has collapsed, had a seizure, has trouble breathing, or can’t be awakened, immediately call emergency services at Large overdoses may result in reversible cardiac conduction defects or dysrhythmias, apnea, coma and seizures.

Allergic Reactions Advise patients to discontinue KAPVAY and seek immediate medical attention if any signs or symptoms of a hypersensitivity reaction occur, such as generalized rash, urticaria, or angioedema [see Warnings and Precautions 5. Symptoms of overdose may include the following: Take clonidine at around the same times every day.

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Titrate slowly and monitor vital signs frequently.

Ask your doctor or pharmacist for a list of these medicines, if you are not sure if your medicine is listed above. Study 1 CLON was a short-term, multi-center, padkage, double-blind, placebo-controlled study of two fixed doses 0. Clonidine is also used and as an aid in smoking cessation therapy and to diagnose pheochromocytoma a tumor that develops on a gland near the kidneys mapvay may cause high blood pressure and fast heart rate.

What special precautions should I follow?

Kapvay | FULL Prescribing Information |

Treatments were separated by one-week washout periods. The impact of renal impairment on the pharmacokinetics of clonidine in children has not been assessed. Clonidine hydrochloride is present in human milk. Patients had been treated with a psychostimulant methylphenidate or amphetamine for four weeks with inadequate response.

Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Your doctor may ask you to check your pulse heart rate daily and will tell you how rapid it should be.